Transplant Pathogen Monitoring


Varicella Zoster Virus (VZV) is a widespread herpes virus responsible for varicella or “chickenpox” in children, and zoster in adults. After solid organ or hematopoietic stem cell transplantation, latent VZV reactivation is frequent, leading to serious skin diseases and diverse complications, especially for young patients without pre-existing immunity to VZV. In the post-transplant period, VZV diagnosis and viral load testing is relevant for patient management, at the onset of suggestive symptoms to confirm the diagnostics.

VZV ELITe MGB® Kit is a real-time PCR assay designed for the detection and quantification of varicella zoster virus DNA. The assay is CE-IVD validated on a large range of sample types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.


Conserved targets · Region of varicella zoster virus open-reading frame 29 gene and human beta-globin gene as an internal control
Easy-to-use · Monoreagent, ready-to-use
Best-in class PCR technology · ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Large range of samples · Whole blood, plasma and cerebrospinal fluid
Integrated workflow · Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance · 98.7% clinical sensitivity and 100% clinical specificity
Quantitative result · Copies/mL (cp/mL)
Storage of standard curve · 60 days
Eluate storage · Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time · Less than 2 minutes per sample from extraction to result analysis
Complete transplant menu · Complete transplant pathogen monitoring range


Ordering Information

Product Name Description Reference
VZV ELITe MGB Kit 4 tubes, 24 reactions each RTS035PLD
VZV ELITe Standard 2 sets of 4 levels, 8 reactions each STD035PLD
VZV ELITe Positive Control 2 tubes, 4 reactions each CTR035PLD
CTRCPE – Internal Control 4 tubes, 12 reactions each CTRCPE


VZV ELITe MGB Kit is also CE-IVD validated with other systems