Transplant Pathogen Monitoring

HEV ELITe MGB® Kit

Hepatitis E (HEV) is an increasing cause of liver infection worldwide, and is generally asymptomatic or sometimes associated with severe symptoms, similar to those observed with hepatitis A. After solid organ transplantation, patients treated with immunosuppressive drugs are especially at high risk of developing HEV infection. Hepatitis E detection by molecular methods is important to diagnose and identify acute and chronic infections.

 

Hepatitis E ELITe MGB® Kit is a real-time PCR assay designed for the detection of Hepatitis E virus belonging to 1, 2, 3, 3 and 4 genotypes. The assay is intended to be used for research-use-only applications (RUO) and has been tested in combination with ELITe InGenius®, a fully automated sample-to-result solution.

 

Benefits 

Conserved targets· ORF-2 region of Hepatitis E gene and genomic RNA of MS2 phage gene as an internal control
One-step format· Reverse transcription and PCR amplification within the same run
Best-in class PCR technology· ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Sample· Plasma
Integrated workflow· Fully automated process for extraction, amplification and result analysis with ELITe InGenius
Eluate storage· Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time· Less than 2 minutes per sample from extraction to result analysis
Complete transplant menu· Complete transplant pathogen monitoring range

 

Ordering Information

Product NameDescriptionReference
HEV ELITe MGB KitHEV PCR MasterMix: 2 tubes, 48 reactions each
HEV PreMix: 2 tubes, 48 reactions each
RT EnzymeMix: 2 tubes, 48 reactions each
RTS130ING
HEV-ELITe Positive Control2 tubes, 5 reactions eachCTR130ING
CTRCPE – Internal Control4 tubes, 12 reactions eachCTRCPE