Respiratory Infections

Products

MDR/MTB ELITe MGB® Kit

Tuberculosis is a major and underdiagnosed health issue commonly caused by species belonging to the Mycobacterium tuberculosis. The steady increase of resistant forms, caused by intensive use of frontline antibio­tics such as rifampicin and isoniazid, is particularly alarming and leads to massive treatment failure. Rapid and reliable detection of patients infected with MTB and resistance to rifampicin and isoniazid, is essential to determine the right therapy and limit the use of inappropriate treatments.

MDR/MTB ELITe MGB® Kit is a real-time PCR assay designed for the simultaneous detection of the DNA of Mycobacterium tuberculosis complex and resistance to rifampicin and isoniazid. The assay is validated in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Benefits

Conserved targets· MTB Complex: IS6110 region repeated sequence
· Rifampicin resistance: rpoB gene hotspot region
· Isoniazid resistance: katG gene and inhA gene regions
· Internal control: artificial DNA sequence
Easy-to-use· Monoreagents, ready to use
Best-in class PCR technology· ELITe MGB® probes designed with Minor Groove Binder technology, Superbases® and Eclipse® Dark Quencher
Sample · Sputum
Integrated workflow· Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance· 100% clinical sensitivity and 98% clinical specificity
Eluate storage· Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time · Less than 2 minutes per sample from extraction to result analysis
Complete respiratory infections menu· Complete respiratory infections range with Respiratory Viral ELITe MGB® Panel and Respiratory Bacterial ELITe MGB® Panel

Ordering Information

Product NameDescription Reference
MDR/MTB ELITe MGB Kit*TB1 Mix:4 tubes, 24 reactions each
TB2 Mix:4 tubes, 24 reactions each
RTS120ING
MDR/MTB ELITe Positive Control*3 tubes, 2 reactions each CTR120ING
CTRCPE – Internal Control4 tubes, 12 reactions each CTRCPE

*available soon

Respiratory Bacterial ELITe MGB® Panel

Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila are common bacteria involved in respiratory infections, and responsible for severe complications, especially in the immunocompromised. Symptoms of respiratory infections are similar, non-specific, and not sufficient to clearly identify the causative agent. Molecular methods are the most efficient solutions to identify the right pathogen and provide an adapted patient treatment.

Respiratory Bacterial ELITe MGB® Panel is a multiplex PCR assay designed to detect and differentiate Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila/Legionella longbeachae DNAs. The assay is  validated on bronchoalveolar lavage samples, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Respiratory Viral ELITe MGB® Panel

Influenza A, influenza B and Respiratory syncytial viruses are the most common cause of acute respiratory infections. These respiratory viruses can also cause serious complications among persons with weak immune systems, such babies and the elderly. Simultaneous detection of Flu A, Flu B and HRSV A/B with molecular testing methods is important, to better manage patients and control infections.

Respiratory Viral ELITe MGB® Panel is a triplex PCR assay designed for the detection of Influenza A and B virus and respiratory syncytial viruses A and B specific genes. The assay is CE-IVD validated on respiratory swab samples, in combination with ELITe InGenius®, a fully automated sample-to-result solution.