Healthcare Associated Infections

Products

Colistin ELITe MGB®Kit

The rapid expansion of Colistin resistance, one of the last resort antibiotics available against multidrug resistant gram-negative bacteria, is of particular concern worldwide. Rapid and reliable detection of Colistin resistance genes mcr-1 and mcr-2 with molecular methods is important to better control infections in healthcare settings.

 

 

Colistin ELITe MGB® Kit is a real-time PCR assay for the detection of plasmidic colistin resistance genes mcr-1 and mcr-2 of Enterobacteriaceae in DNAs samples. The research use only (RUO) assay and has been tested in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Benefits

Conserved targets · regions of mcr-1 and mcr-2 specific genes
Easy-to-use· Monoreagent, ready to use
Best-in class PCR technology· ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Samples· Rectal swabs
Integrated workflow· Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance· 100% clinical sensitivity and 100% clinical specificity
Eluate storage· Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time· Less than 2 minutes per sample from extraction to result analysis
Complete HAI menu· Complete healthcare associated infections testing range with CE-IVD validated ESBL ELITe MGB® Kit, CRE ELITe MGB® Kit, C. difficile ELITe MGB® Kit and MRSA/SA ELITe MGB® Kit

Ordering Information

Product NameDescriptionReference
Colistin ELITe MGB KitMonoreagent: 8 tubes, 12 reactions eachRTS202ING
Colistin ELITe Positive Control3 tubes, 4 reactions each CTR202ING
CTRCPE – Internal Control4 tubes, 12 reactions each CTRCPE

C. difficile ELITe MGB® Kit

Clostridium difficile bacteria are major causes of healthcare associated infections, especially in the elderly or in patients treated by antibiotics. Intensive use of antibiotics can promote C. difficile expansion, leading to severe outcomes. Rapid detection of patients with Clostridium difficile infections in healthcare facilities is crucial, to isolate infected patients, provide an appropriate treatment and proceed to decontamination.

C. difficile ELITe MGB® Kit is a real-time PCR assay designed for the detection and the differentiation of Clostridium difficile toxins A and B DNA, including the hypervirulent epidemic NAP1/BI/027 strain. The assay is CE-IVD validated on stool, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

CRE ELITe MGB® Kit

Carbapenem-Resistant Enterobacteriaceae (CRE) are bacteria resistant to carbapenems, the antibiotics of “last resort”.  CRE are responsible for serious infections much more difficult to treat with higher morbidity and mortality in hospitals. Rapid and reliable Carbapenem-Resistant Enterobacteriaceae detection with molecular methods is crucial to identify infected patients, implement infection measure controls, and avoid outbreak in hospital and healthcare settings.

CRE ELITe MGB® Kit is a multiplex real-time PCR assay designed for the detection and the differentiation of all main relevant classes of Carbapenem-Resistant Enterobacteriaceae genes: KPC (serine carbapenemases genes), NDM, VIM, IMP (metallo beta-lactamases genes), and OXA-48 like (OXA carbapenemases genes). The assay is CE-IVD validated on different samples types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

ESBL ELITe MGB® Kit

Extended Spectrum Beta-Lactamases (ESBLs) are enzymes produced by enterobacteriaceae which are resistant to frequently used antibiotics as penicillin and cephalosporin. ESBL Enterobacteriaceae are responsible for serious infections more difficult to treat, with fewer effective antibiotics to use and higher patient morbidity and mortality. Such patients are generally treated with Carbapenems. Reliable detection of patients infected with resistant bacteria producing ESBLs, is essential to determine the right antibiotic and limit the use of inappropriate treatments.

ESBL ELITe MGB® Kit is a multiplex real-time PCR assay designed for the detection of CTX-M genes, the most prevalent group of ESBL genes in Enterobacteriaceae. The assay is CE-IVD validated on several sample matrices, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

MRSA/SA ELITe MGB® Kit

Methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus (SA) bacteria are major causes of nosocomial infections associated with higher morbidity and significant hospital costs. Rapid and reliable detection of MRSA and SA with molecular methods is important for pre-surgical screening, identification of colonised patients and better control infections in healthcare settings.

MRSA/SA ELITe MGB® Kit is a triplex PCR assay designed for the detection and differentiation of Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus DNAs, based on a unique patented design. The assay is CE-IVD validated on different sample matrices in combination with ELITe InGenius®, a fully automated sample-to-result solution.