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MDR/MTB ELITe MGB® Kit

Tuberculosis is a major and underdiagnosed health issue commonly caused by species belonging to the Mycobacterium tuberculosis. The steady increase of resistant forms, caused by intensive use of frontline antibio­tics such as rifampicin and isoniazid, is particularly alarming and leads to massive treatment failure. Rapid and reliable detection of patients infected with MTB and resistance to rifampicin and isoniazid, is essential to determine the right therapy and limit the use of inappropriate treatments. MDR/MTB ELITe MGB® Kit is a real-time PCR assay designed for the simultaneous detection of the DNA of Mycobacterium tuberculosis complex and resistance to rifampicin and isoniazid. The assay is validated in combination with ELITe InGenius®, a fully automated sample-to-result solution.

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BENEFITS

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Benefits

Conserved targets
  • MTB Complex: IS6110 region repeated sequence
  • Rifampicin resistance: rpoB gene hotspot region
  • Isoniazid resistance: katG gene and inhA gene regions
  • Internal control: artificial DNA sequence
Easy-to-use
  • Monoreagents, ready to use
Best-in class PCR technology
  • ELITe MGB® probes designed with Minor Groove Binder technology, Superbases® and Eclipse® Dark Quencher
Sample
  • Sputum, Urine, BAL, BA, Cavitary fluid, Aspirate Gastric, Tissue/Biopsy
Integrated workflow
  • Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance
  • 100% clinical sensitivity and 98% clinical specificity
Eluate storage
  • Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time
  • Less than 2 minutes per sample from extraction to result analysis
Complete respiratory infections menu
  • Complete respiratory infections range with Aspergillus spp ELITe MGB® Kit, Pneumocystis ELITe MGB® Kit, Respiratory Viral ELITe MGB® Panel and Respiratory Bacterial ELITe MGB® Panel

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