Extended Spectrum Beta-Lactamases (ESBLs) are enzymes produced by enterobacteriaceae which are resistant to frequently used antibiotics as penicillin and cephalosporin. ESBL Enterobacteriaceae are responsible for serious infections more difficult to treat, with fewer effective antibiotics to use and higher patient morbidity and mortality. Such patients are generally treated with Carbapenems. Reliable detection of patients infected with resistant bacteria producing ESBLs, is essential to determine the right antibiotic and limit the use of inappropriate treatments. ESBL ELITe MGB® Kit is a multiplex real-time PCR assay designed for the detection of CTX-M genes, the most prevalent group of ESBL genes in Enterobacteriaceae. The assay is CE-IVD validated on several sample matrices, in combination with ELITe InGenius®, a fully automated sample-to-result solution.


Conserved targets
  • Regions of Extended Spectrum Beta-Lactamase genes of Enterobacteriaceae: CTX-M 1,9,14 and 15 groups and an artificial DNA sequence as an internal control
  • Monoreagent, ready to use
Best-in class PCR technology
  • TaqMan probes designed with Minor Groove Binder technology, Superbases® and Eclipse® Dark Quencher
  • Rectal swabs and blood culture
Integrated workflow
  • Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance
  • 99.3% clinical sensitivity and 100% clinical specificity
Eluate storage
  • Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time
  • Less than 2 minutes per sample from extraction to result analysis
Complete HAI menu
  • CRE ELITe MGB Kit, MRSA/SA ELITe MGB Kit, C. difficile ELITe MGB® Kit and Colistin – R ELITe MGB® Kit

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