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PRODUCT

EBV ELITe MGB® Kit

Epstein–Barr virus (EBV) is a ubiquitous herpesvirus associated with a broad range of clinical manifestations, from infectious mononucleosis to severe complications in immunocompromised individuals. In transplant recipients and other high-risk patients, EBV reactivation or uncontrolled viral replication may contribute to the development of serious disorders such as post-transplant lymphoproliferative disease (PTLD). EBV viral load monitoring is important to diagnose and monitor such complications which are cared for by reducing the patient immunosuppressive treatment. EBV ELITe MGB® Kit is a real-time PCR assay, designed for the detection and quantification of EBV DNA extracted from clinical specimens.

The assay is validated for use with ELITe InGenius® and ELITe BeGenius® instruments for whole blood, plasma and cerebrospinal fluid matrices, and with the MyGenius PRO® instrument for whole blood.

The assay is also validated with the ELITe GALAXY, automated extraction and PCR set-up system and 7500 Fast Dx Real-Time PCR Instrument using whole blood.

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BENEFITS

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Benefits

Target gene
  • Region of the EBNA-1 gene
Easy-to-use
  • Monoreagent, ready-to-use
Kit format
  • 96 tests (4 tubes x 24 tests each)
Type of analysis
  • Quantitative
Validated matrices
  • Whole blood, plasma, and cerebrospinal fluid*
Minimum sample volume required
  • 200 µl for all matrices; 1000 µl for plasma only
Sample-to-Result workflow
  • Fully automated process including extraction, amplification, and result analysis with ELITe InGenius®, ELITe BeGenius® and MyGenius PRO®
Regulatory status
  • Whole process CE-IVD (IVDR) compliant
Trusted technology
  • ELITe MGB® probes designed with Minor Groove Binder technology, Superbases®, and Eclipse® Dark Quencher
Wide panel
  • Comprehensive solution with more than 15 different assays for immunocompromised patients

*The validated associations between instruments and sample matrices should be verified in the product manual.

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