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CRE ELITe MGB® Kit

Carbapenem-Resistant Enterobacteriaceae (CRE) are bacteria resistant to carbapenems, the antibiotics of “last resort”. CRE are responsible for serious infections much more difficult to treat with higher morbidity and mortality in hospitals. Rapid and reliable Carbapenem-Resistant Enterobacteriaceae detection with molecular methods is crucial to identify infected patients, implement infection measure controls, and avoid outbreak in hospital and healthcare settings.

CRE ELITe MGB® Kit is a multiplex real-time PCR assay designed for the detection and the differentiation of all main relevant classes of Carbapenem-Resistant Enterobacteriaceae genes: KPC (serine carbapenemases genes), NDM, VIM, IMP (metallo beta-lactamases genes), and OXA-48 like (OXA carbapenemases genes). The assay is CE-IVD validated on different samples types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

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BENEFITS

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Benefits

Conserved targets
  • Regions of carbapenem resistance genes of Enterobacteriaceae: KPC, NDM, VIM, IMP and OXA-48 like genes and an artificial DNA sequence as an internal control
  • Each family is detected with a specific amplification set
Easy-to-use
  • Monoreagent, ready to use
Best-in class PCR technology
  • ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Samples
  • Rectal swabs and blood culture
Integrated workflow
  • Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance
  • 99.3% clinical sensitivity and 100% clinical specificity
Eluate storage
  • Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time
  • Less than 2 minutes per sample from extraction to result analysis
Complete HAI menu
  • ESBL ELITe MGB® Kit, MRSA/SA ELITe MGB® Kit, C.difficile ELITe MGB® Kit and Colistin – R ELITe MGB® Kit

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