CMV RNA ELITe MGB® Kit

Despite advances in transplantation management, human Cytomegalovirus (hCMV) infection remains a major challenge in both hematopoietic stem cell transplantation (HSCT) and solid organ transplantation (SOT). While CMV DNAemia is currently the gold standard for post-transplant monitoring, its interpretation may become challenging in patients receiving CMV terminase complex inhibitors such as letermovir, where free CMV DNA fragments can remain detectable even in the absence of active viral replication.
In this setting, CMV messenger RNA (mRNA), which is expressed from the earliest stages of infection, may represent a valuable marker of active hCMV replication, providing clinically relevant information to support patient monitoring and therapeutic decision-making. The innovative CMV RNA ELITe MGB® kit is a one-step reverse transcription and Real-Time PCR assay designed for the detection and quantification of human Cytomegalovirus virion mRNA, extracted from clinical specimens.
The assay is validated for use with ELITe InGenius® and ELITe BeGenius® instrument for plasma matrix.