PRODUCT

BCR-ABL P190 ELITe MGB® Kit

The product of the Philadelphia translocation, the BCR/ABL oncogene P190 isoform, is commonly found in acute lymphoid leukemia, a rare disease that can be fatal within a matter of months if untreated. Detection and quantification of P190 BCR-ABL fusion gene, by molecular methods, is crucial for patient management, to initiate the appropriate treatment and measure response to therapy.

BCR-ABL P190 ELITe MGB® Kit is a real-time PCR assay for the detection and quantification of the mRNA of the BCR-ABL t(9;22) translocation of the Philadelphia chromosome, isoform P190 compared to the kinase protein Abelson (ABL) mRNA. The assay has been tested on a large range of sample types with conventional extraction and PCR systems.”

BCR-ABL P190 master mix

Benefits

Conserved targets
  • Fusion gene and BCR-ABL, isoform P190 · human gene ABL
One-step format
  • Reverse transcription and real-time PCR assay within the same run
Best-in class PCR technology
  • ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Large range of samples
  • Peripheral blood samples, medullary blood samples collected in citrate or EDTA, lymphomonocyte or leukocyte suspensions
Instruments
  • Extraction: TRI reagent product (Thermo Fisher Scientific) · Thermal cyclers: ABI 7300 Real-Time PCR system and ABI 7500 series
High performance
  • 96% clinical sensitivity and 100% clinical specificity
Complete Onco-hematology menu
  • Complete Onco-hematology menu with BCR-ABL P210 ELITe MGB® Kit and Philadelphia P210 RNA reference

Let us help you

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