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MGB Alert® JCV
Most people infected with JCV are asymptomatic. In those receiving immunosuppressive therapies e.g., transplant recipients, and in the immunocompromised, JCV can cause progressive multifocal leukoencephalopathy (PML), a neurodegenerative disease that is often fatal.1
Our analyte specific reagents§ feature:
- Thoughtfully designed primers and probes
- Primers and probes manufactured according to FDA and cGMP requirements
MGB probes | DSQ probes | Eclipse Dark Quencher | Duplex Stabilizing Quencher | Pleiades probe chemistry | AquaPhluor® Dyes | Superbases
| Catalog number | Product Name | Reactions | Fluorophore | Product description |
| M800601 | MGB Alert® JCV Primer Mix ASR | 48 | – | Amplifies nucleic acids within the VP1 gene in JC virus |
| M800602 | MGB Alert® JCV Probe Mix ASR | 48 | FAM | Detects nucleic acids within the VP1 gene in JC virus |
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Benefits
Innovative. MGB Alert reagents utilize our original minor groove binder probe technology, and feature flexibility of PCR-based detection and/or melt curve analysis. DSQ Alert™ reagents now incorporate our proprietary duplex stabilizing quencher (DSQ), a next step in MGB probe chemistry.
Flexible. Our reagents can be used on the ELITe InGenius® and ELITe BeGenius™ instrument systems, and on most open channel platforms. Let us help create the right workflow for your lab.
Responsive. We frequently anticipate and nimbly respond to market needs as they arise. Let us know what you’d like to add to your own real-time PCR menu.
Visit egmdx.com to learn more. We offer a full menu of IVD tests, analyte specific reagents (ASRs), and research use only (RUO) materials designed with proprietary chemistries.
1Pietropaolo V, Prezioso C, Bagnato F, Antonelli G. John Cunningham virus: an overview on biology and disease of the etiological agent of the progressive multifocal leukoencephalopathy. New Microbiol. 2018 Jul;41(3):179-186. https://pubmed.ncbi.nlm.nih.gov/29620790/
§Analytical and performance characteristics are not established.
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