Precision Biologics Haemostasis Reagents

Controls & Specialty Plasmas

For more than 25 years, labs have been trusting Precision BioLogic’s integrated line of high-quality, frozen cryocheck™ controls and calibrators to help them deliver consistently accurate results.

Frozen format eliminates reconstitution errors and offers products that are ready to use in minutes

cryocheck Pooled Normal Plasma
Pooled Normal Plasma is comprised of platelet-poor plasma from 20 or more carefully screened male and female donors aged 18 to 66. It is recommended as a normal control for the one stage PT and activated partial thromboplastin time (APTT) assays. It may also be used as an alternative to laboratory collected pools of normal plasma.
Each lot number is verified to be normal for factors II, V, VII, VIII, IX, X, XI, and XII (factor assay value sheet available upon request) as well as fibrinogen
Donors are screened negative for lupus anticoagulants
Source plasmas are screened negative for all FDA-required tests

CCN-10 80 x 1.0 mL

CCN-15 80 x 1.5 mL

CCN-40 80 x 4.0 mL

cryocheck Abnormal 1 Control
cryocheck™ Abnormal 1 Control is intended for use as an abnormal control for one-stage prothrombin time (PT) and activated partial thromboplastin time (APTT) assays.
24-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

CCA1-10 80 x 1.0 mL

cryocheck Abnormal 2 Control
cryocheck™ Abnormal 2 Control is intended for use as an abnormal control for one-stage prothrombin time (PT) and activated partial thromboplastin time (APTT) assays.
24-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

CCA2-10 80 x 1.0 mL

cryocheck Normal Reference Plasma
cryocheck™ Normal Reference Plasma is intended for use as an assayed calibrator for all parameters listed below. Reference values are assigned by an independent, internationally-recognized reference laboratory, using international reference standards (where available). Assigned value, unit, and method used are indicated on the Assay Certificate provided with each lot number.

8-hour stability once thawed if refrigerated at 2 to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

CCNRP-05 25 x 0.5 mL
CCNRP-10 25 x 1.0 mL

The following assays may be calibrated with cryocheck Normal Reference Plasma:

Fibrinogen
Factor II
Factor V
Factor VII
Factor VIII:C
Factor IX
Factor X
Factor XI
Factor XII
Factor XIII
Prekallikrein
vWF: Antigen
vWF: Ristocetin Cofactor
Antithrombin Activity
Antithrombin Antigen
Plasmin Inhibitor
Plasminogen
Protein C Activity
Protein C Antigen
Protein S Activity
Protein S Free
Protein S Total

cryocheck Abnormal 1 Reference Control
cryocheck™ Abnormal 1 Reference Control is intended for use as an assayed borderline abnormal control for parameters listed on the Assay Certificate. Reference values are assigned by an independent, internationally-recognized reference laboratory, using international reference standards (where available).

8-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

ARP1-05 25 x 0.5 mL
ARP1-10 25 x 1.0 mL

cryocheck Abnormal 2 Reference Control
cryocheck™ Abnormal 2 Reference Control is intended for use as an assayed pathological abnormal control for parameters listed on the Assay Certificate. Reference values are assigned by an independent, internationally-recognized reference laboratory, using international reference standards (where available).

8-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

 

 

ARP2-10 25 x 1.0 mL

cryocheck Reference Control Normal
cryocheck™ Reference Control Normal is intended for use as an assayed normal control for parameters listed on the Assay Certificate. Reference values are assigned by an independent, internationally recognized reference laboratory, using international reference standards (where available).

8-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

RCN-05 25 x 0.5 mL
RCN-10 25 x 1.0 mL

cryocheck Lupus Positive Control
cryocheck™ Lupus Positive Control is intended for use as a positive control in assays for lupus anticoagulant (LA). cryocheck Lupus Positive Control contains citrated human plasma collected from donors that have tested positive in accordance with the revised criteria of the SSC Subcommittee for the Standardization of Lupus Anticoagulants.
8-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

CCLP-05 25 x 0.5 mL
CCLP-10 25 x 1.0 mL

cryocheck Weak Lupus Positive Control
cryocheck™ Weak Lupus Positive Control is intended for use as a positive control in assays for lupus anticoagulant (LA). It contains citrated human plasma collected from donors that have tested positive in accordance with the revised criteria of the SSC Subcommittee for the Standardization of Lupus Anticoagulants. cryocheck Weak Lupus Positive Control is a weak positive LA control that challenges an assay’s sensitivity to LA, allowing users to be confident that weak LA positive patient samples will be accurately detected.

8-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

CCWLP-05 25 x 0.5 mL
CCWLP-10 25 x 1.0 mL

cryocheck Lupus Negative Control
cryocheckTM Lupus Negative Control is intended for use as a negative control in assays for lupus anticoagulant (LA). It contains citrated human plasma collected from donors that have tested negative in accordance with the revised criteria of the SSC Subcommittee for the Standardization of Lupus Anticoagulants.

8-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial

Source plasmas are screened negative for all FDA-required tests

CCLN-05 25 x 0.5 mL
CCLN-10 25 x 1.0 mL

cryocheck Low Fibrinogen Control
cryocheck™ Low Fibrinogen Control is intended for use as an abnormal control in quantitative fibrinogen assays. It is derived from citrated, pooled normal plasma, and adjusted to exhibit hypofibrinogenemic characteristics. Each lot number is tested by the Clauss Fibrinogen method.

72-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

CCLF-10 80 x 1.0 mL

cryocheck Heparin Control
cryocheck™ Heparin Control is intended for use as an abnormal control for activated partial thromboplastin time (APTT) assays. It is made from citrated, pooled normal plasma, which is treated with sodium heparin salt.
8-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Source plasmas are screened negative for all FDA-required tests

CCH-10 80 x 1.0 mL

cryocheck APCR Positive Control
cryocheck™ APCR Positive Control is intended for use as a positive control in clot-based screening assays for Activated Protein C Resistance (APCR) and may be used to supplement or replace in-house controls. Plasma is collected from donor(s) confirmed heterozygous for factor VLeiden mutation by polymerase chain reaction-based analysis.
8-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial

APCR-05 25 x 0.5 mL

cryocheck CorPac™
Reagents
Precision BioLogic’s line of frozen cryocheck™ reagents includes factor deficient plasmas along with dRVVT reagents. Our factor deficient plasmas are immunodepleted, platelet-poor, and tested by both antigenic and functional assays to have less than 1% of the relevant coagulation factor.*

Frozen format eliminates reconstitution errors and offers products that are ready to use in minutes. All our reagents have a long shelf life of three years from date of manufacture.

cryocheck LA Check™
cryocheck™ LA Check is a dilute Russell’s Viper Venom Time (dRVVT) reagent intended to screen for the presence of lupus anticoagulant (LA) in citrated human plasma. The reagent contains Russell’s viper venom, phospholipids, and anti-heparin agents. cryocheck LA Check can be used in conjunction with cryocheck LA Sure to confirm the presence of LAs.

Easily adapted for use on most instruments
Unused reagent may be refrozen
48-hour stability once thawed if refrigerated at 2 °C to 8 °C in the original capped vial
Screening (cryocheck LA Check) and confirmatory (cryocheck LA Sure) reagents are manufactured to strict tolerances and do not need to be “matched” by specific lot numbers

cryocheck LA Sure™
cryocheck Platelet Lysate
cryocheck Factor II Deficient Plasma
cryocheck Factor V Deficient Plasma
cryocheck Factor VII Deficient Plasma
cryocheck Factor VIII Deficient Plasma
cryocheck Factor IX Deficient Plasma
cryocheck Factor X Deficient Plasma
cryocheck Factor XI Deficient Plasma
cryocheck Factor XII Deficient Plasma
cryocheck Prekallikrein Deficient Plasma
cryocheck Prekallikrein Deficient Plasma is prepared from a prekallikrein-deficient donor.

Building on the success of our cryocheck™ frozen calibrators, controls and reagents, Precision BioLogic offers a line of diagnostic kits. Like all our cryocheck products, our kits are frozen, eliminating reconstitution errors and offering fast and easy preparation.

cryocheck Clot C™
cryocheck Clot S™
C & S Diluent
cryocheck Chromogenic Factor VIII
cryocheck Factor VIII Inhibitor Kit
cryocheck Hex LA™