Respiratory Infections

MTB ELITe MGB® Kit

The Mycobacterium Tuberculosis Complex (MTBC) is a genetically related group of Mycobacterium species responsible for tuberculosis in humans, one of the top 10 causes of death worldwide. Tuberculosis is primarily a pulmonary disease transmitted via contaminated aerosol droplets but has many clinical manifestations, affecting bone, the central nervous system and leading to severe outcomes if untreated. Rapid and reliable detection of Mycobacterium tuberculosis species with molecular methods is crucial, especially in immunocompromised subjects, to provide an appropriate therapy.

MTB ELITe MGB® Kit is a qualitative PCR assay for the detection of Mycobacterium tuberculosis Complex DNAs (M.tuberculosis, M.africanum, M.bovis, M. bovis BCG, M.microti and M.canettii). The assay is CE-IVD validated on bronchoalveolar lavages and bronchial aspirates with automated extraction and PCR systems.

 

Benefits

Conserved targets · Region of MTB complex IS6110 gene and human beta-globin gene as an internal control
Easy-to-use · Monoreagent, ready-to-use
Best-in class PCR technology · ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Samples · Bronchoalveolar lavage (BAL) and bronchial aspirate (BA)
Instruments · Extraction: NucliSENS easy MAG
· Thermal cyclers: ABI 7500 Fast DX Real Time PCR instrument and 7500 Real Time PCR System
High performance · MTB complex: 97.6% clinical sensitivity and 97.3% clinical specificity
Complete Respiratory Infection menu · Complete respiratory Infections range with Respiratory Viral ELITe MGB® Panel, Respiratory Bacterial ELITe MGB® Panel and MDR/MTB ELITe MGB Kit*

*available soon

Ordering Information

Product Name Description Reference
MTB ELITe MGB Kit Monoreagent: 4 tubes, 25 reactions each RTS120PLD
MTB ELITe-Positive Control MTB Positive Control: 2 tubes, 7 reactions each CTR120PLD