Meningitis Viral 1 ELITe MGB® Panel

HSV1, HSV2 and VZV are common causes of viral meningitis in adolescents and adults. These infections can cause similar symptoms to bacterial meningitis, and induce serious inflammations, like herpetic meningo-encephalitis, a therapeutic emergency resulting in important sequelae and a high mortality rate if untreated. Rapid detection of HSV1, HSV2 and VZV with molecular testing methods is crucial to identify the viral agent involved, rule out a bacterial infection and provide an adapted treatment.

Meningitis Viral 1 ELITe MGB® Panel is a triplex PCR assay designed for the detection of type 1 and 2 herpes virus and varicella zoster virus specific genes in one single reaction. The assay is CE-IVD validated on cerebrospinal fluid samples, in combination with ELITe InGenius®, a fully automated sample-to-result solution.


Conserved targets · HSV1: glycoprotein G gene DNA
· HSV2: glycoprotein D gene DNA
· VZV: UL 21 and ORF 62 genes DNA
· Internal control: murine cytomegalovirus DNA sequence
Best-in class PCR technology · TaqMan probes designed with Minor Groove Binder technology
Sample · Cerebrospinal fluid
Integrated workflow · Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance · HSV1: 96.9% clinical sensitivity and 100% clinical specificity
· HSV2: 100% clinical sensitivity and 100% clinical specificity
· VZV: 100% clinical sensitivity and 100% clinical specificity
Eluate storage · Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time · Less than 2 minutes per sample from extraction to result analysis
Complete meningitis menu · Complete Meningitis testing with Meningitis Viral 2 ELITe MGB® Panel (Enterovirus, Parechovirus, Adenovirus) and Meningitis Bacterial ELITe MGB® Panel* (N. meningitides, S. pneumoniae, H .influenza)

*available in 2018


Ordering Information

Product Name Description Reference
Meningitis Viral 1 ELITe MGB Panel MV1 Primer and Probe Mix: 2 tubes, 48 reactions each
MV1 Buffer Mix: 2 tubes, 48 reactions each
MV1 Enzyme: 2 tubes, 48 reactions each
Meningitis Viral 1 ELITe Positive Control 2 tubes, 6 reactions each CTR507ING
IC500 – Internal Control 3 tubes, 32 reactions each IC500