Transplant Pathogen Monitoring

HHV8 ELITe MGB® Kit

Human herpes virus 8 (HHV8) is an oncogenic virus highly prevalent in Mediterranean and Sub-Saharian countries. Latent reactivation of HHV8 after solid organ transplantation, especially after kidney transplantation, can generate a life-threatening skin cancer called ‘Kaposi sarcoma’. HHV8 detection and quantification is crucial for patient management in order to provide, as soon as possible, a specific anticancer treatment and discontinue immunosuppressive therapies.

HHV8 ELITe MGB® Kit is a real-time PCR assay designed for the detection and quantification of human herpes virus 8 DNA. The assay is CE-IVD validated on different sample types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Benefits

Conserved targets · Regions of human herpes virus 8 open-reading frame 16 gene and human beta-globin gene as an internal control
Easy-to-use · Monoreagent, ready-to-use
Best-in class PCR technology · ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Samples · Whole blood and plasma
Integrated workflow · Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance · 100% clinical sensitivity and 100% clinical specificity
Quantitative result · Copies/mL (cp/mL)
Storage of standard curve · 60 days
Eluate storage · Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time · Less than 2 minutes per sample from extraction to result analysis
Complete transplant menu · Complete transplant pathogen monitoring range

 

Ordering Information

Product Name Description Reference
HHV8 ELITe MGB Kit 4 tubes, 24 reactions each RTS038PLD
HHV8 ELITe Standard 2 sets of 4 levels, 8 reactions each STD038PLD
HHV8 ELITe Positive Control 4 tubes, 2 reactions each CTR038PLD
CTRCPE – Internal Control 4 tubes, 12 reactions each CTRCPE

 

HHV8 ELITe MGB Kit is also CE-IVD validated with other systems