Transplant Pathogen Monitoring

EBV ELITe MGB® Kit

Epstein-Barr Virus (EBV) is a widespread herpesvirus, generally asymptomatic or sometimes responsible for mild infection like mononucleosis. After solid organ or hematopoietic stem cell transplant, EBV reactivation is a common cause of malignant transformation, called Post-Transplant Lymphoproliferative Disorder “PTLD”. EBV viral load monitoring is important to diagnose, and monitor such complications which are cared for by reducing the patient immunosuppressive treatment.

EBV ELITe MGB® Kit is a real-time PCR assay designed for the detection and quantification of Epstein-Barr virus DNA. The assay is CE-IVD validated on a large range of sample types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Benefits

Conserved targets · Region of Epstein-Barr virus nuclear antigen 1 gene and human beta-globin gene as an internal control
Easy-to-use · Monoreagent, ready-to-use
Best-in class PCR technology · ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Large range of samples · Whole blood, plasma and cerebrospinal fluid
Integrated workflow · Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance · 100% clinical sensitivity and 96% clinical specificity
Quantitative result · International units (IU/mL) correlated to the 1st WHO International standard for Human EBV for NAAT (NIBSC Code 09/260)
· Copies/mL (cp/mL)
Storage of standard curve · 60 days
Eluate storage · Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time · Less than 2 minutes per sample from extraction to result analysis
Complete transplant menu · Complete transplant pathogen monitoring range

 

Ordering Information

Product Name Description Reference
EBV ELITe MGB Kit 4 tubes, 24 reactions each RTS020PLD
EBV ELITe Standard 2 sets of 4 levels, 8 reactions each STD020PLD
EBV ELITe Positive Control 2 tubes, 4 reactions each CTR020PLD
CTRCPE – Internal Control 4 tubes, 12 reactions each CTRCPE

 

EBV ELITe MGB Kit is also CE-IVD validated with other systems