Molecular Diagnostics

Leading-edge solutions enabling better medical decisions.
ELITechGroup is a leading PCR innovator with the revolutionary Minor Groove Binder (MGB) technology and a global solution provider for Molecular Diagnostics.
Our products deliver superior performance, enabling more accurate diagnoses for patient treatment and monitoring of organ and stem cells transplant, immunocompromised patients, infectious diseases, healthcare associated Infections, onco-hematology and human genetics.
ELITechGroup Molecular Diagnostics has pioneered developments in molecular diagnostics, bringing trusted results to laboratories, giving clinicians the tools to make fast and accurate medical decisions and improve clinical outcomes.

Products

HHV8 ELITe MGB® Kit

Human herpes virus 8 (HHV8) is an oncogenic virus highly prevalent in Mediterranean and Sub-Saharian countries. Latent reactivation of HHV8 after solid organ transplantation, especially after kidney transplantation, can generate a life-threatening skin cancer called ‘Kaposi sarcoma’. HHV8 detection and quantification is crucial for patient management in order to provide, as soon as possible, a specific anticancer treatment and discontinue immunosuppressive therapies.

HHV8 ELITe MGB® Kit is a real-time PCR assay designed for the detection and quantification of human herpes virus 8 DNA. The assay is CE-IVD validated on different sample types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Coagulation ELITe MGB® Kit

Factor V, Factor II, and Methylene Tetrahydropholate Reductase (MTHFR) genes are involved in the coagulation system. Single nucleotide polymorphism variants (SNP) of those genes are associated with higher risk of thrombosis and embolisms. Variant detection by genetic testing is important in patients with hypercoagulability to provide adapted therapy.

Coagulation ELITe MGB® Kit is a real-time PCR assay designed for the detection and the allelic discrimination of the main variants associated with thrombosis and embolisms: Factor V G1691A (Leiden), Factor II G20210A and MTHFR C677T. The 3 variants are detected in one single reaction by melt-curve analysis. The assay is CE-IVD validated on blood samples, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

C. difficile ELITe MGB® Kit

Clostridium difficile bacteria are major causes of healthcare associated infections, especially in the elderly or in patients treated by antibiotics. Intensive use of antibiotics can promote C. difficile expansion, leading to severe outcomes. Rapid detection of patients with Clostridium difficile infections in healthcare facilities is crucial, to isolate infected patients, provide an appropriate treatment and proceed to decontamination.

C. difficile ELITe MGB® Kit is a real-time PCR assay designed for the detection and the differentiation of Clostridium difficile toxins A and B DNA, including the hypervirulent epidemic NAP1/BI/027 strain. The assay is CE-IVD validated on stool, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Respiratory Viral ELITe MGB® Panel

Influenza A, influenza B and Respiratory syncytial viruses are the most common cause of acute respiratory infections. These respiratory viruses can also cause serious complications among persons with weak immune systems, such babies and the elderly. Simultaneous detection of Flu A, Flu B and HRSV A/B with molecular testing methods is important, to better manage patients and control infections.

Respiratory Viral ELITe MGB® Panel is a triplex PCR assay designed for the detection of Influenza A and B virus and respiratory syncytial viruses A and B specific genes. The assay is CE-IVD validated on respiratory swab samples, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

ESBL ELITe MGB® Kit

Extended Spectrum Beta-Lactamases (ESBLs) are enzymes produced by enterobacteriaceae which are resistant to frequently used antibiotics as penicillin and cephalosporin. ESBL Enterobacteriaceae are responsible for serious infections more difficult to treat, with fewer effective antibiotics to use and higher patient morbidity and mortality. Such patients are generally treated with Carbapenems. Reliable detection of patients infected with resistant bacteria producing ESBLs, is essential to determine the right antibiotic and limit the use of inappropriate treatments.

ESBL ELITe MGB® Kit is a multiplex real-time PCR assay designed for the detection of CTX-M genes, the most prevalent group of ESBL genes in Enterobacteriaceae. The assay is CE-IVD validated on several sample matrices, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Respiratory Bacterial ELITe MGB® Panel

Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila are common bacteria involved in respiratory infections, and responsible for severe complications, especially in the immunocompromised. Symptoms of respiratory infections are similar, non-specific, and not sufficient to clearly identify the causative agent. Molecular methods are the most efficient solutions to identify the right pathogen and provide an adapted patient treatment.

Respiratory Bacterial ELITe MGB® Panel is a multiplex PCR assay designed to detect and differentiate Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila/Legionella longbeachae DNAs. The assay is  validated on bronchoalveolar lavage samples, in combination with ELITe InGenius®, a fully automated sample-to-result solution.