Molecular Diagnostics

Leading-edge solutions enabling better medical decisions.
ELITechGroup is a leading PCR innovator with the revolutionary Minor Groove Binder (MGB) technology and a global solution provider for Molecular Diagnostics.
Our products deliver superior performance, enabling more accurate diagnoses for patient treatment and monitoring of organ and stem cells transplant, immunocompromised patients, infectious diseases, healthcare associated Infections, onco-hematology and human genetics.
ELITechGroup Molecular Diagnostics has pioneered developments in molecular diagnostics, bringing trusted results to laboratories, giving clinicians the tools to make fast and accurate medical decisions and improve clinical outcomes.

Products

Norovirus ELITe Panel

Noroviruses are highly contagious viruses and the main causative agents of acute gastroenteritis accounting for over 267 million infections worldwide. Molecular testing is the preferred method to effectively diagnose norovirus infections and prevent person-to-person transmission.

Norovirus ELITe Panel is a one step, reverse-transcription and real-time PCR assay designed for the detection of Norovirus RNA. The assay is CE-IVD validated on a large range of sample types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Benefits

Conserved targets · ORF1 and ORF2 junction region of Norovirus gene and an internal control
One-step format · Reverse transcription and PCR amplification within the same run
Sample· Stool
Integrated workflow· Fully automated process for extraction, amplification and result analysis with ELITe InGenius
Eluate storage · Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time · Less than 2 minutes per sample from extraction to result analysis
Complete menu · Complete Gastrointestinal pathogen range*: Enteric Viral Panel, Enteric Bacterial Panel and Enteric Parasitic Panel

*in development

Ordering Information

Product NameDescriptionReference
Norovirus ELITe PanelNV Reaction Mix: 2 tubes, 48 reactions each
NV Enzyme Mix: 1 tube, 96 reactions
NV Positive Control: 2 tubes, 6 reactions each
NV Internal Control: 3 tubes, 32 reactions each
RTK561ING

Colistin ELITe MGB®Kit

The rapid expansion of Colistin resistance, one of the last resort antibiotics available against multidrug resistant gram-negative bacteria, is of particular concern worldwide. Rapid and reliable detection of Colistin resistance genes mcr-1 and mcr-2 with molecular methods is important to better control infections in healthcare settings.

 

 

Colistin ELITe MGB® Kit is a real-time PCR assay for the detection of plasmidic colistin resistance genes mcr-1 and mcr-2 of Enterobacteriaceae in DNAs samples. The research use only (RUO) assay and has been tested in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Benefits

Conserved targets · regions of mcr-1 and mcr-2 specific genes
Easy-to-use· Monoreagent, ready to use
Best-in class PCR technology· ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Samples· Rectal swabs
Integrated workflow· Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance· 100% clinical sensitivity and 100% clinical specificity
Eluate storage· Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time· Less than 2 minutes per sample from extraction to result analysis
Complete HAI menu· Complete healthcare associated infections testing range with CE-IVD validated ESBL ELITe MGB® Kit, CRE ELITe MGB® Kit, C. difficile ELITe MGB® Kit and MRSA/SA ELITe MGB® Kit

Ordering Information

Product NameDescriptionReference
Colistin ELITe MGB KitMonoreagent: 8 tubes, 12 reactions eachRTS202ING
Colistin ELITe Positive Control3 tubes, 4 reactions each CTR202ING
CTRCPE – Internal Control4 tubes, 12 reactions each CTRCPE

MDR/MTB ELITe MGB® Kit

Tuberculosis is a major and underdiagnosed health issue commonly caused by species belonging to the Mycobacterium tuberculosis. The steady increase of resistant forms, caused by intensive use of frontline antibio­tics such as rifampicin and isoniazid, is particularly alarming and leads to massive treatment failure. Rapid and reliable detection of patients infected with MTB and resistance to rifampicin and isoniazid, is essential to determine the right therapy and limit the use of inappropriate treatments.

MDR/MTB ELITe MGB® Kit is a real-time PCR assay designed for the simultaneous detection of the DNA of Mycobacterium tuberculosis complex and resistance to rifampicin and isoniazid. The assay is validated in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Benefits

Conserved targets· MTB Complex: IS6110 region repeated sequence
· Rifampicin resistance: rpoB gene hotspot region
· Isoniazid resistance: katG gene and inhA gene regions
· Internal control: artificial DNA sequence
Easy-to-use· Monoreagents, ready to use
Best-in class PCR technology· ELITe MGB® probes designed with Minor Groove Binder technology, Superbases® and Eclipse® Dark Quencher
Sample · Sputum
Integrated workflow· Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance· 100% clinical sensitivity and 98% clinical specificity
Eluate storage· Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time · Less than 2 minutes per sample from extraction to result analysis
Complete respiratory infections menu· Complete respiratory infections range with Respiratory Viral ELITe MGB® Panel and Respiratory Bacterial ELITe MGB® Panel

Ordering Information

Product NameDescription Reference
MDR/MTB ELITe MGB Kit*TB1 Mix:4 tubes, 24 reactions each
TB2 Mix:4 tubes, 24 reactions each
RTS120ING
MDR/MTB ELITe Positive Control*3 tubes, 2 reactions each CTR120ING
CTRCPE – Internal Control4 tubes, 12 reactions each CTRCPE

*available soon

Adenovirus ELITe MGB® Kit

Adenoviruses are important causes of infections in both immunocompetent and immunocompromised individuals, and leading causes of morbidity and mortality, especially in children.
Latent adenovirus reactivation, or transmission during transplantation, can be responsible for disseminated infection and graft loss.
Adenovirus detection and viral load monitoring, by molecular methods, is essential to quickly set up an appropriate antiviral treatment and prevent serious complications.
Adenovirus ELITe MGB® Kit is a real-time PCR assay designed for the detection and quantification of Adenovirus DNA. The assay is CE-IVD validated on different sample types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

Aspergillus ELITe MGB® Kit

Aspergillosis is the most common cause of fungal infection among stem cell and solid organ transplant recipients, resulting in high mortality if untreated. Patients with weakened immune system and lung diseases are at higher risk of developing severe outcomes. Early detection and quantification of Aspergillus with molecular methods is crucial to isolate infected patients and provide an appropriate treatment.

 

Aspergillus ELITe MGB® Kit is a quantitative PCR assay for the detection and quantification of the DNA of the Aspergillus genus:  Aspergillus niger, Aspergillus nidulans, Aspergillus terreus, Aspergillus flavus, Aspergillus versicolor and Aspergillus glaucus.

 

Benefits

Conserved targets· Region of Aspergillus rDNA18s gene and human beta-globin gene as an internal control
Easy-to-use· Monoreagent, ready-to-use
Best-in class PCR technology· ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher
Samples· Bronchoalveolar lavage (BAL) and bronchial aspirate (BA)
Instruments· Thermal cyclers: ABI 7500 Fast DX Real Time PCR instrument and 7500 Real Time PCR System
High performance· 100% clinical sensitivity and 97.8% clinical specificity
Complete Respiratory Infection menu· Complete respiratory Infections range with Respiratory Viral ELITe MGB® Panel, Respiratory Bacterial ELITe MGB® Panel and MDR/MTB ELITe MGB Kit*

 

Ordering Information

Product Name Description Reference
Aspergillus spp. ELITe MGB Kit4 tubes, 25 reactions eachRTS110PLD
Aspergillus spp. ELITe Standard 2 sets of 4 levels, 8 reactions each STD110PLD

 

 

BCR-ABL P190 ELITe MGB® Kit

The product of the Philadelphia translocation, the BCR/ABL oncogene P190 isoform, is commonly found in acute lymphoid leukemia, a rare disease that can be fatal within a matter of months if untreated. Detection and quantification of P190 BCR-ABL fusion gene, by molecular methods, is crucial for patient management, to initiate the appropriate treatment and measure response to therapy.

 

BCR-ABL P190 ELITe MGB® Kit is a real-time PCR assay for the detection and quantification of the mRNA of the BCR-ABL t(9;22) translocation of the Philadelphia chromosome, isoform P190 compared to the kinase protein Abelson (ABL) mRNA. The assay has been tested on a large range of sample types with conventional extraction and PCR systems.

BCR-ABL P210 ELITe MGB® Kit

The product of the Philadelphia translocation, the BCR/ABL oncogene P210 isoform, is typically found in chronic myelogenous leukemia, and in acute lymphoid and myeloid leukemia, causing the cells to divide uncontrollably and inducing severe outcomes among patients. Detection and quantification of P210 BCR-ABL fusion gene, by molecular methods, is crucial for patient management, to initiate the appropriate treatment, measure the response to therapy and predict relapse

 

BCR-ABL P210 ELITe MGB® Kit is a real-time PCR assay for the quantification of the mRNA of the BCR-ABL rearrangement, t(9;22) translocation of the Philadelphia chromosome, isoform P210 compared to the mRNA of the gene coding the kinase protein Abelson (ABL) mRNA. The assay has been tested on a large range of sample types with conventional extraction and PCR systems.

BKV ELITe MGB® Kit

BK Virus (BKV) is a highly prevalent and asymptomatic polyomavirus in the general population, and a major cause of renal infection in immunocompromised patients. Latent BKV is frequently reactivated after kidney and hematopoietic stem cell transplantation, leading to renal dysfunction and potentially graft loss. BKV viral load monitoring is crucial for patient management in order to prevent renal diseases and transplant failure.

BKV ELITe MGB® Kit is a real-time PCR assay designed for the detection and quantification of BK virus DNA. The assay is CE-IVD validated on diverse range of sample types, in combination with ELITe InGenius®, a fully automated sample-to-result solution.